microRNA Diagnostics and Therapeutics

Sempere Laboratory
The Sempere Laboratory pursues complementary lines of translational research to explain the etiological role of microRNAs and unravel microRNA regulatory networks during carcinogenesis. The lab investigates these questions in clinical samples and pre-clinical models of breast cancer and pancreatic cancer.

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Last week, Dr. Sempere presented "Intraductal approaches for breast cancer prevention and treatment" at VARI's Research in Progress seminar series. His talk highlighted recent results from a translational project in the lab for an audience of fellow VARI scientists and students. This project is supported by a VAI Employee Impact Campaign and a VARI Faculty Innovation awards. This is a collaborative project with the participation of local clinicians and MSU faculty.” ... See MoreSee Less

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The Sempere Lab welcomed Josh Schipper earlier this summer. Josh is a West Michigan native who has recently returned with his family to the snowy north from warmer climates. He graduated from Grand Valley State University, and went on to obtain his PhD in biochemistry from North Carolina State University and was a postdoc at Duke University. His research has focused on drug design and studying the structure/function relationship of caspases in relation to cell death, and understanding how complex transcription factor binding preferences play a role in gene regulation for the E2F family of cell cycle regulators and other transcription factors. ... See MoreSee Less

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Our new review on exosomal microRNAs in breast cancer is published in the latest issue of Cancers. To learn more about this work please visit this site: www.mdpi.com/2072-6694/9/7 ... See MoreSee Less

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