Lead Investigator Bio

Sempere Laboratory
Lorenzo Sempere, Ph.D.
Assistant Professor, Program in Skeletal Disease and Tumor Microenvironment, Center for Cancer and Cell Biology

Areas of expertise: microRNAs, breast cancer, pancreatic cancer, tumor microenvironment, pre-clinical models,  ISH/IHC assays


Dr. Lorenzo Sempere is originally from Elche, a sunny city in southeastern Spain with one of largest palm tree groves in the world. He obtained his B.S. in biochemistry at Universidad Miguel Hernández and trained in the laboratory of Victor Ambros, co-discoverer of microRNAs, at Geisel School of Medicine at Dartmouth College. Dr. Sempere initiated his translational cancer research in the laboratory of Charles Cole with a Susan G. Komen for the Cure postdoctoral fellowship and continued to climb the academic ladder at Dartmouth in the laboratory of Murray Korc with a Laurie and Paul MacCaskill PanCAN-AACR Career Development award. He eventually established his independent research group thanks to R21 and R03 grants from the National Cancer Institute at the National Institutes of Health. After 14 years at Dartmouth, Dr. Sempere joined Van Andel Research Institute as assistant professor and as a faculty member at Van Andel Institute Graduate School.

Dr. Sempere has worked in the microRNA field since the molecules’ discovery in 2001. He has experience and expertise as author, reviewer and journal editor in diverse areas of microRNA research, including evolutionary and developmental biology, molecular and cellular biology, and immunology and cancer biology.